Serotype-specific immune responses to pneumococcal conjugate vaccine among children are significantly correlated by individual: Analysis of randomized controlled trial data.

Vaccine(2018)

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摘要
•Some individuals have stronger immune responses against all serotypes in PCV.•Increasing time since vaccination was associated decreasing antibody levels.•Older participants tended to have higher antibody levels than younger participants.
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关键词
Streptococcus pneumoniae,Pneumococcal conjugate vaccine,Antibody response,Nasopharyngeal colonization
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