Diisobutylaluminum borohydride: An efficient reagent for the reduction of tertiary amides to the corresponding amines under ambient conditions

Rachel Snelling,Gabriella Amberchan,Angel Resendez, Chris L. Murphy,Lauren Porter,Bakthan Singaram

Tetrahedron Letters（2017）

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摘要

•Development of reducing agent diisobutylaluminum borohydride.•Tertiary amides reduced to the corresponding amine under ambient conditions.•No column purification technique required for isolation of amine product.

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关键词

Aluminum,Boron,Borohydride,Ambient,Amide,Amine,Hydride,Reduction

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