High genetic variability of norovirus leads to diagnostic test challenges.

Ran Zhuo, Joanne Cho,YuanYuan Qiu,Brendon D Parsons,Bonita E Lee,Linda Chui,Stephen B Freedman,Xiaoli Pang

Journal of Clinical Virology（2017）

引用 11|浏览5

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摘要

•Luminex GPP is a widely used multi-analyte molecular assay for syndromic testing of GI pathogens.•Luminex GPP was less sensitive than an in-house RT-qPCR in the detection of norovirus genogroup II.•Discordant norovirus results in samples with low Ct values were studied.•The sensitivity of Luminex GPP was lowest for NoV GII.2 and failed to detect some GII.2 strains.

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关键词

Luminex GPP,In-house GVP,Norovirus,GII.2,Discordance

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