Breast screening: What can the interval cancer review teach us? Are we perhaps being a bit too hard on ourselves?

•The study shows the simple step of blinding readers to cancer location leads to reduction in the ascribed missed cancer rate of 17%.•If methodology applied by Payne et al. [15], whereby interval cancers were missed when detected by 2 readers retrospectively, the missed cancer rate is 39%.•The commonest unanimously and retrospectively detected sign of a “missed” cancer was microcalcification and the most challenging was asymmetric density.