Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling

NATURE(2017)

引用 119|浏览10
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摘要
Random mutagenesis in haploid human cells coupled to quantitative protein measurements with different antibodies is used as a readout for individual cellular phenotypes.
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关键词
Epistasis,Growth factor signalling,Quantitative trait
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