Novel Annonaceous acetogenins from Graviola (Annona muricata) fruits with strong anti-proliferative activity

Shi Sun,Jingchun Liu,Xiuxiu Sun,Wenjun Zhu,Fei Yang, Lisa Felczak,Q. Ping Dou,Kequan Zhou

Tetrahedron Letters（2017）

引用 18|浏览6

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摘要

•Three new and two known C35 Annonaceous acetogenins compounds were isolated from Graviola fruit.•New compound structures were elucidated using spectral methods as well as chemical modification.•These acetogenins demonstrated potent anti-proliferation of human prostate cancer PC-3 cells.

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关键词

Annonamuricin,Annona muricata,Human prostate cancer PC-3 cells,Anonnonaceous acetogenins

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