Up-regulated BAFF and BAFF receptor expression in patients with intractable temporal lobe epilepsy and a pilocarpine-induced epilepsy rat model.

Limin Ma,Ruohan Li,Hao Huang,Jinxian Yuan,Shu Ou,Tao Xu,Xinyuan Yu,Xi Liu,Yangmei Chen

Seizure（2017）

引用 6|浏览3

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摘要

•BAFF and BAFFR are increased in TLE patients and pilocarpine-induced epilepsy rats.•BAFF and BAFFR are mainly co-localized within neurons, but not in astrocytes.•BAFF and BAFFR may promote the epileptogenesis by immune and inflammatory responses.

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关键词

BAFF,BAFFR,Temporal lobe epilepsy,Immune and inflammatory reaction,NF-κB pathway

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