Surgery And Definitive Chemoradiation (Crt) For Locally Advanced Oropharyngeal Cancer And Impact Of Transoral Robotic Surgery (Tors).

6055 Background: TORS is an emerging modality for oropharyngeal cancer. However, many patients require adjuvant therapy based on high-risk pathologic findings. We compared control rates of TORS to CRT. Methods: A retrospective review was performed evaluating all consecutive patients treated in our department for oropharyngeal cancer from January 2010 through December 2013. All patients treated with definitive CRT or surgical resection with adjuvant RT +/- chemotherapy. Results: 103 total patients identified among whom 40 were resected (33/40 TORS). Majority of patients were stage IVA (86%). 92% (37/40) of patients in the surgery group were T1/T2 vs 36% (23/63) in CRT group. p16 associated with improved locoregional control (LRC) (91% vs 43%, p=0.035). 22/40 resected patients required adjuvant radiation with chemotherapy (trimodality) due to 16/40 with extracapsular extension, 5/40 with positive margins and 2/40 with both. TORS had decreased rate of positive margins (9.1%) vs radical resection (29%). T4a p...