Apoptosis of peritoneal leucocytes during early stages of Fasciola hepatica infections in sheep.

A Escamilla,R Pérez-Caballero,R Zafra,M J Bautista,I L Pacheco,M T Ruiz,M S Martínez-Cruz,A Martínez-Moreno,V Molina-Hernández,J Pérez

Veterinary Parasitology（2017）

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摘要

•F. hepatica induces peritoneal leucocytes apoptosis in sheep from 1dpi onwards.•Apoptosis of peritoneal leucocytes may allow the larvae to evade the host immune response.•Peritoneal leucocyte apoptosis is detected earlier with annexin V than caspase-3.

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关键词

Apoptosis,Caspase-3,Annexin-V,Peritoneal leucocytes,Fasciola hepatica,Sheep

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