Tissue differences in DNA methylation changes at AHRR in full term low birth weight in maternal blood, placenta and cord blood in Chinese.
Placenta(2017)
摘要
•The newborns born FT-LBW had significantly lower AHRR DNA methylation at one CpG site in cord blood.•The mothers who had FT-LBW babies had significantly higher AHRR DNA methylation at five CpG sites in maternal blood.•AHRR methylation at CpG 13 in cord blood and maternal blood independently associated with FT-LBW in different ways.•No significant association was observed between FT-LBW and the AHRR DNA methylation in placenta.
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关键词
AHRR,DNA methylation,Low birth weight,Cord blood,Placenta,Maternal blood
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