Enrichment of short mutant cell-free DNA fragments enhanced detection of pancreatic cancer.

Xiaoyu Liu,Lingxiao Liu,Yuan Ji,Changyu Li,Tao Wei,Xuerong Yang,Yuefang Zhang,Xuyu Cai,Yangbin Gao,Weihong Xu,Shengxiang Rao,Dayong Jin,Wenhui Lou,Zilong Qiu,Xiaolin Wang

EBioMedicine（2019）

引用 56|浏览53

暂无评分

摘要

We found that the small mutant fragments are prevalent in early-stage patients, which provides strong evidence for fragment size-based detection of pancreatic cancer. The new pipeline enhanced our understanding of cfDNA biology and provide new insights for liquid biopsy.

查看译文

关键词

Pancreatic cancer,Cell-free DNA,Fragmentation,Tissue biopsy,Diagnosis and prognosis

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要