Chemical ribosylation of 5-substituted 1,2,4-triazole-3-carboxylates.

Alexander N Prutkov,Mikhail V Chudinov,Andrey V Matveev,Lyubov E Grebenkina,Yulia V Berezovskaya

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS（2019）

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摘要

The chemical ribosylation pathways of 5-substituted-1,2,4-triazole-3-carboxylates are discussed. For the products of the chemical synthesis of the 3(5)-alkyl- or 3(5)-aryl-substituted ribavirin analogues the anomer configuration and isomer composition were determined.

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关键词

Ribavirin analogues,ribosylation,nucleoside synthesis

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