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Expression of MMP-2 and TIMP-1 during rapid maxillary expansion in rats.

Archives of Oral Biology, (2017): 30-35

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com www.sciencedirect.com

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Matrix metalloproteinaseTissue inhibitors of metalloproteinaseMidpalatal sutureTensile forceBone remodeling

Abstract

•Midpalatal expansion induced bone formation along the edges of the palatal bone.•Expression of MMP-2 and TIMP-1 were significantly increased by expansion.•The ratio of MMP-2/TIMP-1 was significantly enhanced during expansion.•MMP-2 and TIMP-1 regulates midpalatal suture remodeling during maxillary expansion.

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