Asymmetric Synthesis of 2,3,4-Trisubstituted Piperidines

SYNTHESIS-STUTTGART(2017)

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摘要
Two different organocatalytic approaches for the asymmetric synthesis of 2,3,4-trisubstituted piperidines were developed. Both approaches were based on an aza-Michael addition followed by cyclization and gave products in high enantiomeric excess.
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关键词
organocatalysis,asymmetric catalysis,trisubstituted piperidines,aza-Michael addition,cyclization
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