Qualitative and quantitative analyses of Compound Danshen extract based on 1H NMR method and its application for quality control

Journal of Pharmaceutical and Biomedical Analysis(2016)

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摘要
•1H NMR spectroscopy combined with chemometrics method was developed for qualitative and quantitative analysis of Compound Danshen Dripping Pills.•Three phenolic acids were determined simultaneously by using 1H NMR method.•Hat matrix and Mahalanobis distance were used to define the threshold value for quality evaluation.
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关键词
1H NMR spectroscopy,Compound danshen dripping pill,Chemometrics method,Quality control,Chinese herbal medicine
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