Inflammatory parameters associated with systemic reactogenicity following vaccination with adjuvanted hepatitis B vaccines in humans.

Vaccine(2019)

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摘要
•Reactogenicity and inflammatory markers evaluated after HBsAg-adjuvanted vaccines.•Significant associations between systemic symptoms and IL-6 and IFN signals revealed.•Similar inflammatory signals were shown to be associated with the adaptive response.
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关键词
HBsAg-AS01B adjuvanted vaccine,Reactogenicity,Innate response,Association with systemic symptoms,IFNγ signals,IL-6 signals
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