Characterization of strain-specific phenotypes associated with knockout of dense granule protein 9 in Toxoplasma gondii.

Huanping Guo,Yang Gao,Honglin Jia,Paul Franck Adjou Moumouni,Tatsunori Masatani,Mingming Liu,Seung-Hun Lee,Eloiza May Galon,Jixu Li,Yongchang Li,Maria Agnes Tumwebaze,Byamukama Benedicto,Xuenan Xuan

Molecular and Biochemical Parasitology（2019）

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摘要

•First time GRA9 knockout in the type II PLK strain.•PLKΔGRA9 parasites showed defect in plaque formation.•GRA9 may be involved in parasite egress and virulence in a strain-specific manner.

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关键词

Toxoplasma gondii,GRA9,Knockout,Growth,Egress,Virulence

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