Factors affecting KRAS mutation detection in colorectal cancer tissue.

Hyon-Goo Yun,Hyun Joo Lee,Bo-Ra Kim,Joo-Hee Lee,Jun-Hyeong Lee,Mi-Yeon Lee,Dong-Hoon Kim,Jin Hee Sohn,Seoung Wan Chae,In Gu Do,Sung-Im Do,Kyungeun Kim

Pathology - Research and Practice（2019）

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摘要

The biopsy specimens showed better sample DNA quality for KRAS mutation test compared to resection specimens. In a routine diagnostic pathology setting, the cold ischemia time was an important factor affecting DNA quality and the formalin fixation had a wide time range for optimal DNA quality.

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关键词

Ct,FFPE,H&E,NBF

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