Clinical and Economic Analysis of Morphine Versus Fentanyl in Managing Ventilated Neonates With Respiratory Distress Syndrome in the Intensive Care Setting.

Dina Abushanab,Omar Alsoukhni,Fouad AbouNahia,Daoud Al-Badriyeh

Clinical Therapeutics（2019）

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摘要

This is the first cost-effectiveness evaluation of morphine versus fentanyl in the NICU. Morphine significantly improved the relieve of pain over fentanyl. It had 98% probability of dominance over fentanyl. Results in this study support the use of morphine over fentanyl as first-line monotherapy with MV in NICU settings.

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关键词

analgesia,cost-effectiveness,decision analytic model,intensive care unit,neonates,Premature Infant Pain Profile

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