Neuroprotective potential of GDF11 in experimental intracerebral hemorrhage in elderly rats.

Journal of Clinical Neuroscience(2019)

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摘要
•Neurological impairment after elderly ICH could be attenuated by GDF11.•The mechanism for antioxidant effect of GDF11 in post-ICH is proposed.•The mechanism for mitochondrial protective effect of GDF11 after ICH is proposed.
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关键词
Intracerebral hemorrhage,Growth Differentiation Factor 11,Apoptosis,Inflammation,Oxidative stress,Mitochondria injury
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