No effect of riluzole and memantine on learning deficit following Quinpirole sensitization - An animal model of obsessive-compulsive disorder.

Martina Janikova,Hana Brozka,Dominika Radostova,Jan Svoboda,Ales Stuchlik

Physiology & Behavior（2019）

引用 6|浏览11

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摘要

•Quinpirole sensitization produces hyperlocomotion and deficits in place learning.•Cognitive effects of quinpirole are independent of the hyperactivity.•Neither memantine nor riluzole alleviated the cognitive deficit induced by quinpirole.

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关键词

Quinpirole,Memantine,Riluzole,Obsessive-compulsive disorder,Active allothetic place avoidance task

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