Prolongation of skin graft survival in mice by an azaphenothiazine derivative

Jolanta Artym,Maja Kocięba,Ewa Zaczyńska,Iwona Kochanowska,Michał Zimecki,Wojciech Kałas,Leon Strządała,Ewa Zioło,Małgorzata Jeleń,Beata Morak-Młodawska,Krystian Pluta

Immunology Letters（2019）

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摘要

•DQT azaphenothiazine prolongs skin allograft survival in mice.•DQT preferentially causes loss of CD3-CD8+CD11b + cells in human PBMC.•DQT elicits expression of caspase 8 and p53 proteins in Jurkat cells.

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关键词

Azaphenothiazine,Skin allograft,p53,Caspase 8,Mixed lymphocyte reaction,CD3-CD8+ cells

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