In vivo multiplexed OPT and FLIM OPT of an adult zebrafish cancer disease model

Sunil Kumar,Nicola Lockwood,M-C. Ramel,Teresa Correia,Matthew J. Ellis,Yuriy Alexandrov,Natalie Andrews,R. Patel,Laurence Bugeon,Maggie J. Dallman,Sebastian Brandner,Simon R. Arridge,Matilda Katan,James McGinty,Paul Frankel,Paul M. W. French

Cancer（2016）

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摘要

We report angular multiplexed OPT and FLIM OPT applied to in vivo imaging of cancer and FRET biosensors in adult zebrafish. Multiple-spectral 3-D datasets of entire adult zebrafish can be acquired in 3 minutes.

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