Choroid plexus transcriptome and ultrastructure analysis reveals a TLR2-specific chemotaxis signature and cytoskeleton remodeling in leukocyte trafficking.

Amin Mottahedin,C Joakim Ek,Katarina Truvé,Henrik Hagberg,Carina Mallard

Brain, Behavior, and Immunity（2019）

引用 31|浏览13

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摘要

•Choroid plexus is a major route of TLR2-induced leukocyte infiltration to the CNS.•TLR2-specific chemotaxis signature at choroid plexus revealed by RNA seq.•TEM and RNA seq suggest cytoskeleton remodeling at choroid plexus.

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关键词

Choroid plexus,Inflammation,Infection,Leukocyte migration,Cytoskeleton,Basement membrane,Remodeling,Toll-like receptor,Inositol,Micall2

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