Generation and characterization of a unique panel of anti-adalimumab specific antibodies and their application in therapeutic drug monitoring assays.

Sumin Bian,Thomas Van Stappen,Filip Baert,Griet Compernolle,Els Brouwers,Sophie Tops,Annick de Vries,Theo Rispens,Jeroen Lammertyn,Séverine Vermeire,Ann Gils

Journal of Pharmaceutical and Biomedical Analysis（2016）

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摘要

Diagram 1, flowchart with an overview of the key trials. The abbreviations used are as follows: ADM, adalimumab; MA, monoclonal antibody; MA-ADM, monoclonal antibodies towards adalimumab; TNF, tumor necrosis factor.

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关键词

MA,MA-ADM,TNFα,TDM,PCA

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