Cronic non-bacterial osteomyelitis (CNO) in a cohort of pediatric patients: clinical, biological and radiological response to treatment with Anakinra

M Pardeo,D Pires Marafon,V Messia,R Nicolai,C Bracaglia,F de Benedetti,A Insalaco

Pediatric Rheumatology（2015）

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摘要

Chronic nonbacterial osteomyelitis (CNO) is the most common autoinflammatory bone disorder in childhood (1). Diagnostic information is provided by TC-99 bone scintigraphy (BS) and/or whole body MRI. Non-steroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, bisphosphonates and tumour necrosis factor inhibitors have been used until now with variable response (2).

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关键词

Glucocorticoid,Erythrocyte Sedimentation Rate,Inflammatory Marker,Bone Lesion,Bone Scintigraphy

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