Two novel antiviral terpenoids from the cultured Perovskia atriplicifolia
Tetrahedron(2015)
摘要
Two novel terpenoids, named norperovskatone (1), biperovskatone (2) were isolated from the cultured Perovskia atriplicifolia, together with five known compounds. Compound 1 was a novel C18 nor-diterpenoid featuring a unique seco-ring C. Compound 2 was an unusual dimer including two different diterpenoid units. The structures of the two novel compounds were established by comprehensive spectroscopic analysis, as well as by crystal X-ray diffractions. All of the isolates were evaluated for their anti-HBV activities. Compounds 1 and 2 were found to possess remarkable anti-HBV activity.
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关键词
Perovskia atriplicifolia,Terpenoids,Anti-HBV
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