Case Of Autoimmune Polyglandular Syndrome Type 2: How We Uncovered The Diagnosis

A 24-year-old man with no significant medical history presented to the medical clinic with vomiting and giddiness for 2days, loss of appetite for 1month and progressive fatigability for the preceding 4months. On examination, he was found to be hypotensive and was admitted to the hospital for work-up. Considering his abnormal labs and physical findings, he was worked up and was diagnosed with primary adrenal insufficiency. On further work-up for the aetiology of his Addison's disease, he was found to have concurrent autoimmune thyroiditis and vitiligo. A final diagnosis of autoimmune polyglandular syndrome type 2 was made. The patient was started on hormone replacement therapy and reported improvement of symptoms on 3-month follow-up visit.