The immune-metabolic regulatory roles of epoxyeicosatrienoic acids on macrophages phenotypic plasticity in obesity-related insulin resistance

Meiyan Dai,Lujin Wu,Ling Tu,Xizhen Xu,Dao Wen Wang

Prostaglandins & Other Lipid Mediators（2018）

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摘要

•We briefly summarize the macrophages recruitment, infiltration and polarization in obese mice.•We elaborate the relationship of CYP epoxygenases, EETs, sEH and metabolic diseases.•We discuss the importance roles of EETs on macrophages phenotypic plasticity in obesity-related insulin resistance.

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关键词

Epoxyeicosatrienoic acids,Macrophage polarization,Inflammation,Insulin resistance

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