ABC transporters as cancer drivers: Potential functions in cancer development

Biochimica et Biophysica Acta (BBA) - General Subjects(2019)

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摘要
•ABC transporters play a key role in cancer chemoresistance.•ABC transporters efflux bioactive molecules in cancer cells.•Pharmacological targeting of ABC transporters should be revisited in cancer therapy.
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关键词
ATP-binding cassette (ABC) transporters,Cancer biology,Chemoresistance,Cell signalling,Lipid transport
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