Calibrate: Intensive Profiling Of Circulating Tumour Dna (Ctdna) From Patients Participating In Experimental Therapeutics Trials Including Mutational Profiles And Copy Number Changes.

Javier Garcia-Corbacho,Florent Mouliere,Hedley Carr,James Anthony Morris, Francesco Marrass,Davina Gale,Sanjeev Kumar,Mirela Hategan, Maricica Zabrautanu,William Dott,Elizabeth A. Harrington,Brian Dougherty,J. Carl Barrett,Bristi Basu,James D. Brenton,Carlos Caldas,Duncan I. Jodrell,Simon Pacey,Nitzan Rosenfeld,Richard D. Baird

JOURNAL OF CLINICAL ONCOLOGY（2016）

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摘要

11530Background: Serial analysis of plasma ctDNA with next generation sequencing could be used to identify patients for matched molecular therapies, to monitor the relative abundance of mutations o...

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关键词

tumour dna,ctdna,mutational profiles,experimental therapeutics trials

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