GxE effects of FKBP5 and traumatic life events on PTSD: A meta-analysis
Journal of Affective Disorders(2019)
摘要
•Aggregate FKBP5 gene effect found in GxE when pooled across all four SNPs.•SNP by trauma effects found for rs1360780, rs3800373, rs9296158, rs9470080 on PTSD.•Failed to find evidence for heterogeneity for any of the four SNPs.•First study to quantify an aggregate gene effect of FKBP5 in a GxE analysis of PTSD.
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关键词
Posttraumatic stress,Trauma,FKBP5,GxE,Alcohol
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