The Notch pathway regulatory protein MIB1 is a novel gene for nonsyndromic bicuspid aortic valve

J. Albuisson, I. Gabay,G. Goudot, J. M. Mazzella,B. Loeys,A. Rossi,T. Mirault,R. Durst,D. Gilon,E. Messas

European Heart Journal（2018）

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摘要

Objective: Bicuspid aortic valve (BAV) is the most common congenital heart malformation (>1%). Patients with BAV are at risk to develop complications, some are life threatening. Previous studies ha...

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