Abstract 16351: Arrhythmic Events in Brugada Syndrome: A Nation-Wide Israeli Survey of the Clinical Characteristics, Treatment and Long-Term Follow-Up (ISRABRU-VF)

Background: Since the first report on Brugada syndrome (BrS), only sparse information has been reported on the detailed characteristics and management of the small subset of patients who had an arrhythmic event (AE). We conducted the first nationwide comprehensive survey focused on the detailed clinical, diagnostic work up, electrophysiological (EP) characteristics and long term management of BrS patients who have had an AE. Methods: All 21 Israeli EP units were invited to participate in the survey if they have treated patients with BrS who had suffered a cardiac arrest (CA) (lethal or aborted)(group 1) or experienced appropriate therapy for VF/VT events after prophylactic ICD implantation (group 2). Analysis included all eligible BrS patients. Results: A total of 31 patients met the inclusion criteria from the entire country: 25 in group 1 and 6 in group 2. In group 1, 96% of patients were male; mean age at CA was 38 years (range 13-84). Nine (36%) patients presented with arrhythmic storm and 3 (12%) had...