Bone metabolism in pediatric burned patients: A review

•This review examines 11 randomized, placebo-controlled prospective clinical trials in pediatric burns between 1995 and 2017, which include approximately 250 burned pediatric subjects in total.•These studies were conducted to evaluate the impact of burn injury on markers of bone formation and bone metabolism, and some trials analyzed current therapy regimens such as pamidronate and vitamin D.•It is recommended that all children, following hospital discharge after receiving treatment for severe burn injury, should receive, at a minimum, a daily dose of multivitamin that contains 400 IU/day of vitamin D.