In vitro response of bone marrow mesenchymal stem cells (hBMSCs) on laser-induced periodic surface structures for hard tissue replacement: Comparison between tantalum and titanium

Optics and Lasers in Engineering(2018)

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摘要
•Laser induced periodic surfaces structure (LIPSS) were fabricated on tantalum and titanium surfaces.•We have demonstrated in vitro that LIPSS are an efficient option to increase osteoblastic differentiation.•LIPSS created increase statistically cell metabolism and similar inflammatory response to the material.•Collagen is produced in more quantity and cells differentiate to osteoblast easily.
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