Carboline alkaloids and isocoumarins from the wasp pathogenic fungus Ophiocordyceps sphecocephala BCC 2661

Jittra Kornsakulkarn,Siriporn Saepua,Sukitaya Veeranondha,Pranee Rachtawee,Masahiko Isaka,Chawanee Thongpanchang

Phytochemistry Letters（2018）

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摘要

•The constituents of fungus Ophiocordyceps sphecocephala BCC 2661 were investigated.•Five new and two new naturally occurring sphecolines A–G were isolated.•Three known β-carboline alkaloids and four known isocoumarins were also isolated.•Sphecolines A and C exhibited cytotoxic activity against NCI-H187 cell lines.

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关键词

Carboline alkaloids,Insect-pathogenic fungi,Ophiocordyceps sphecocephala,Bioactive secondary metabolites

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