Therapeutic intratracheal application of a lytic phage against Acinetobacter baumannii lung infection in mice

Lung and airway infections by multidrug-resistant bacteria including Acinetobacter baumannii are increasingly causes of concern. High specificity of bacteriophages and their effectivity in lysis make phage therapy attractive to overcome this problem. However, phages need to be properly chosen and characterized according to quality standards, and preparations must be highly purified.