Polyphenolic derivatives from mango (Mangifera Indica L.) modulate fecal microbiome, short-chain fatty acids production and the HDAC1/AMPK/LC3 axis in rats with DSS-induced colitis

•The pro-autophagic activity of mango polyphenols in a DSS-treated rat model.•Mango beverage induces metabolite- and butyrate-producing gut microbiota.•Mango beverage induces the concentration of butyrate and valerate in fecal samples.•Microbial metabolites from mango polyphenols downregulate HDAC1 and upregulate AMPK and LC3.