WHO/ILO work-related burden of disease and injury: Protocol for systematic reviews of exposure to long working hours and of the effect of exposure to long working hours on stroke.

•WHO and ILO are developing a joint methodology for estimating the national and global work-related burden of disease and injury•A large network of experts is contributing to this WHO/ILO joint methodologywith two systematic reviews described in this protocol.•The authors will systematically review studies on occupational exposure to long working hours (Systematic Review 1).•They will also systematically review and meta-analyse estimates of the effect of long working hours on stroke (Systematic Review 2).•The authors will develop both systematic reviews in tandem and in a harmonized way, using the Navigation Guide systematic review methodology as an organizing framework.