P53 and L1 cell adhesion molecule (L1CAM) protein expression and mRNA transcriptome analysis in endometrial cancer

Objective: Both p53 and L1 cell adhesion molecule (L1CAM) immunohistochemical (IHC) staining have been shown as prognostic markers of poor outcome in endometrial carcinomas. Few studies have looked at correlation of these markers with protein expression and mRNA transcriptome levels. This study aims to investigate the overlap in protein expression and transcriptome profiles of these two prognostic markers in endometrial cancer.