Cold isostatic pressing of hydrating calcium sulfate as a means to produce parenteral slow-release drug formulations

In the present study, cold isostatic pressing of hydrating biocompatible inorganic materials was used to encapsulate active substance in a highly dense microstructure of bioresorable/biodegradable material. This forms the basis in the NanoZolid® technology. It was shown that such microstructures can be used to produce slow-release parenteral formulations for long-term drug release.