Impact of Coronary Artery Aneurysms in Myocardial Deformation of Convalescent Kawasaki Disease Patients

Background: Abnormal strain, independent of coronary involvement, has been reported in the acute phase of KD. However, there is limited data about the impact of coronary aneurysms in myocardial deformation during the convalescent phase of KD. Objective: To perform a comprehensive assessment of myocardial deformation in patients with KD during the convalescent phase and assess for the effect of coronary artery aneurysms. Methods: KD patients with echocardiograms performed during the convalescent phase (u003e42 days from fever onset to study date) between 8/2013 -11/2014, and with adequate images for analysis with two-dimensional speckle tracking echocardiography (2DSTE) were included. Demographic, clinical, 2D and 2DSTE parameters were measured, including left ventricular global longitudinal strain (GLS), global circumferential strain (GCS) and strain rate (SR), torsion and right ventricular longitudinal strain (RLS) and SR. The patients with and without aneurysms were compared using Chi-square and T-test. Lin...