Anti-mycobacterial haliclonadiamine alkaloids from the Okinawan marine sponge Haliclona sp. collected at Iriomote Island

Delfly B. Abdjul,Akiho Yagi,Hiroyuki Yamazaki,Ryota Kirikoshi,Ohgi Takahashi,Michio Namikoshi,Ryuji Uchida

Phytochemistry Letters（2018）

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摘要

•Two new halichondriamine derivatives were isolated from an Okinawan marine sponge Haliclona sp.•The structures of the new alkaloids were elucidated based on their NMR spectra.•These new compounds showed anti-Mycobacterium avium complex (MAC) activity.

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关键词

Halichondriamine,Haliclonadiamine,Marine sponge Haliclona sp,Antimycobacterial substance

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