A review of brain insulin signaling in mood disorders: From biomarker to clinical target

Thanh Thanh L. Nguyen, Lily C. Chan, Kristin Borreginne,Rajas P. Kale,Chunling Hu,Susannah J. Tye

Neuroscience & Biobehavioral Reviews（2018）

引用 26|浏览8

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摘要

•Central insulin signaling is an important moderator of synaptic plasticity.•Central insulin regulates mood, memory and cognition.•Stress and inflammation are important common pathways in mood and metabolic disorders.

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关键词

Mood disorder,Insulin signaling,Metabolism,Homeostasis,Stress,HPA axis,Neuroinflammation,Allostatic load

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