DNA-grafted hemin with preferable catalytic properties than G-quadruplex/hemin for fluorescent miRNA biosensing

Jia Li,Taixian Yuan,Tiantian Yang,Lulu Xu,Lutan Zhang,Lizhen Huang,Wei Cheng,Shijia Ding

Sensors and Actuators B: Chemical（2018）

引用 18|浏览4

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摘要

•The catalytic properties and analytical performance of novel DNA-grafted Hemin and classical G4/hemin was compared in detail.•DNA-grafted Hemin has lower background, higher catalytic rate, better oxidation tolerance than G4/hemin.•DNA-grafted Hemin also shows higher sensitivity and better dose-response ability for fluorescent biosensing.

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关键词

Biomimetic enzyme,Catalytic activity,G-quadruplex/Hemin,DNA-grafted hemin,Biosensing

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