Total synthesis of Crotogossamide using an on-resin concomitant cyclization/cleavage reaction

Christopher Bérubé,Alexandre Borgia,Gaëlle Simon,Daniel Grenier,Normand Voyer

Phytochemistry Letters（2018）

引用 4|浏览9

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摘要

•Expedient Crotogossamide synthesis by on-resin concomitant cyclization/cleavage.•Antibacterial and anti-biofilm activity of Crotogossamide were investigated.•Efficient synthetic strategy towards cyclic peptide phytochemicals using oxime resin.

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关键词

Crotogossamide,Cyclic peptides,Macrocycles,Oxime resin,Peptide synthesis

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