Platform for Image-Guided Noninvasive Brain Delivery of Magnetic Particles: Concept and Technical Progress

We present an innovative combined imaging/manipulation platform to administer, drive, and concentrate nimble magnetic nanoparticles (MNPs) into a desired target in the brain. MNPs may carry useful payloads, such as agents for chemotherapy, genetic therapy, or radiation therapy. Imaging is provided by a novel head-dedicated magnetic resonance imaging system that uses ultrasteep and ultrafast magnet...