Enhanced Fluorescence Spectroscopy And Imaging Immunoassay Using Biological Photonic Crystals

Kenny Squire,Xianming Kong,Paul LeDuff,Gregory L. Rorrer,Alan X. Wang

2018 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO)（2018）

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摘要

Utilizing nature-created photonic crystals, diatoms, we developed immunoassay with efficiently enhanced fluorescence signals. Testing on standard antibody-antigen models achieved unprecedented detection limits of 10(-16) M and 10(-14) M using fluorescence spectroscopy and fluorescence imaging respectively.

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关键词

fluorescence imaging,enhanced fluorescence spectroscopy,imaging immunoassay,biological photonic crystals,unprecedented detection limits,fluorescence signals,antibody-antigen models

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