Secretins revealed: structural insights into the giant gated outer membrane portals of bacteria
Current Opinion in Structural Biology(2018)
摘要
•Secretins are outer membrane pores that passage large macromolecular substrates.•Recent cryo-EM structures reveal a unique, double-walled β-barrel architecture.•Central secretin domain is conserved across various bacterial secretion systems.•Additional motifs common to the secretin family clarify assembly and function.
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